For laboratory research use only. Not for human or veterinary use, and not evaluated by the FDA. Documentation shown is supplier-provided.

01 · The vial
Labelled with compound, concentration, lot, and research-use-only status.
Research Recovery
TB-500
5mg, with its supplier Certificate of Analysis published before you order. Without sourcing roulette, unlabelled vials, or crypto-only checkout.
- Supplier COA on every batch, published on this page, readable before you pay.
- Identity you can verify, CAS 885340-08-9, molecular formula and weight listed, cross-checkable on PubChem.
- No testing claims we cannot back, Provyd runs no in-house testing and says so, documentation is supplier-provided.
- Card checkout, US dispatch, tracked, shipment protection included on every order.
For in-vitro laboratory research use only. Not for human or veterinary use.
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Free shipment protection on every order.
For laboratory research use only. Not for human or animal use.
Questions on documentation? Open the COA Center
48
Studies cited
every DOI verified
12
Compounds documented
with primary literature
99%+
Supplier-stated purity
per batch COA
100%
Orders tracked
shipment protection included
Before you order
Is documentation included?
Yes, a supplier COA is published for every batch and can be viewed before you order.
Do you test it yourselves?
No. Provyd runs no in-house or independent testing, and all documentation is supplier-provided.
Is this for human use?
No. Every compound is sold strictly for in-vitro laboratory research.
How fast does it ship?
Orders dispatch from the US with tracking, typically within one business day of ordering.
Can I pay by card?
Yes, standard card checkout with a verified researcher account, and no crypto is required.
What if it arrives damaged?
Shipment protection covers replacement, with the details set out in our guarantee.
Certificate of Analysis
Certificate of Analysis
Supplier-provided documentation
The details below reflect what a supplier COA reports. Provyd does not run its own laboratory testing and does not claim independent or third-party verification. Read every value as a supplier statement, and confirm it against the document supplied with your order.
- Purity (HPLC)
- As stated on supplier COA
- Identity (MS)
- Mass-confirmed on supplier COA
- Net peptide content
- As stated on supplier COA
- Heavy metals
- Per supplier documentation
- Sterility
- Per supplier documentation
- Endotoxin
- Per supplier documentation
Placeholder structure shown for demonstration. Specific purity percentages and lot numbers appear only on the supplier document itself, not as Provyd-tested figures.
View COA CenterInspect it yourself
Six things worth checking on any research-chemical order, and what you get here versus what the category typically does.

Provyd
Aluminium crimp seal intact and unbroken, stopper embossed. A seal that arrives compromised is grounds for replacement.
Typical research-chemical vendor
Loose or re-crimped caps are common, with no stated policy if the seal arrives broken.
Describes common practices in the research-chemical category, not any specific company. Provyd performs no independent or third-party testing, and all documentation referenced is supplied by the manufacturer.
Frequently researched together
Sibling concentrations and adjacent references researchers commonly study alongside this one.
Compound information
TB-500 5mg is a research-use-only peptide reference in the Research Recovery category. The 5mg concentration is suitable for controlled catalog comparison and supplier-document review.
Researchers often compare TB-500 with BPC-157, blend formats, and vehicle controls in structured research models. Assessment should focus on reference identity, concentration, and supplier-provided documentation.
Researchers commonly compare against
- Sibling concentrations of the same compound
- Adjacent Research Recovery references
- Vehicle and control materials
- Supplier-provided documentation and lot records
Molecular profile
- Type
- Research Recovery
- Compound
- TB-500
- Concentration
- 5mg
- CAS number
- 885340-08-9
- Molecular formula
- Not listed
- Molecular weight
- ≈ 889 (acetate salt varies) g/mol
- Sequence
- Thymosin β4 active fragment
Reference identifiers are shown for research reference only. Verify them against the supplier-provided COA.
Storage & stability
Store according to the supplier-provided documentation. Keep sealed, protected from light, and logged against lot and concentration in your inventory records.
Published literature
Peer-reviewed research on this compound, cited so you can read the primary sources yourself. Every DOI and PMID below was checked to resolve.
State of the evidence
Full-length thymosin beta-4 has completed phase 1 safety trials and small phase 2 trials in dry eye disease and venous ulcers; no human efficacy trials identified for musculoskeletal, tendon or athletic recovery indications. TB-500 is a synthetic partial fragment and has not itself been studied in published human trials.
- Human clinical trialAnnals of the New York Academy of Sciences · 2010
A randomized, placebo-controlled, single and multiple dose study of intravenous thymosin beta4 in healthy volunteers
Ruff D, et al.
In 40 healthy volunteers, synthetic thymosin beta-4 given intravenously at 42 to 1260 mg as single doses and daily for 14 days reported no dose-limiting toxicities or serious adverse events, with dose-proportional pharmacokinetics.
- Human clinical trialCornea · 2015
Thymosin β4 significantly improves signs and symptoms of severe dry eye in a phase 2 randomized trial
Sosne G, et al.
In a small phase 2 trial, thymosin beta-4 eye drops (RGN-259) reported a 35.1% reduction in ocular discomfort and a 59.1% reduction in total corneal fluorescein staining at day 56 versus vehicle control.
- Human clinical trialAnnals of the New York Academy of Sciences · 2010
The effect of thymosin treatment of venous ulcers
Guarnera G, et al.
In a phase 2 dose-escalation study of 73 patients with venous stasis ulcers, topical thymosin beta-4 at 0.03% was associated with complete wound healing within 3 months in about 25% of patients, with a safety profile comparable to placebo.
- Human clinical trialJournal of Cellular and Molecular Medicine · 2021
A first-in-human, randomized, double-blind, single- and multiple-dose, phase I study of recombinant human thymosin β4 in healthy Chinese volunteers
Wang X, et al.
In 84 healthy volunteers, recombinant human thymosin beta-4 at 0.05 to 25.0 microgram/kg reported mild-to-moderate adverse events with no dose-limiting toxicities or serious adverse events and no obvious accumulation after 10 days of dosing.
These references are provided as scientific context on the compound for qualified researchers. They describe published research findings, not results from Provyd products, and are not a representation that any product will produce any outcome. Provyd sells materials for in-vitro laboratory research use only. Nothing here is medical advice or an endorsement of human or veterinary use.
Catalog Experience Reviews
Reviews cover ordering, documentation, labeling, shipping, and support, not product outcomes.
Demo seed reviews, not verified customer outcomes
Documentation easy to locate
Supplier-provided documentation was easy to find and the concentration was clearly labeled on the catalog page.
Order records were clear
Checkout was simple and the order records arrived clearly itemized with lot and concentration noted.
Research-use labeling is upfront
Research-use-only labeling and supplier sourcing were stated plainly. No overclaiming, which I appreciate.
Our guarantee
Ordered with confidence, or we make it right
Four commitments that cover how your order arrives and what documentation comes with it. Materials are supplied for laboratory research use only.
Shipment protection on every order
If your order is damaged, lost, or stolen in transit, we replace it at no cost to you.
Documentation guarantee
If the supplier COA for your batch turns out to be unavailable, you get a full refund.
Labelling accuracy
If the vial does not match the compound and concentration shown on the listing, we replace it or refund it.
Claims window and evidence
Send photo evidence within 10 days of delivery. Opened or reconstituted vials are not eligible.
Provyd runs no in-house or independent testing. All documentation referenced here is supplier-provided.
Important research notice
All products sold by Provyd are intended strictly for in-vitro laboratory research use only. They are not for human or animal consumption and are not drugs, foods, cosmetics, or dietary supplements. They are not intended to diagnose, treat, cure, or prevent any disease and have not been evaluated by the U.S. Food and Drug Administration. Documentation shown is supplier-provided unless otherwise stated.





